Antimicrobial resistance characteristics of multidrug resistance and extended-spectrum beta-lactamase producing Escherichia coli from several dairy farms in Probolinggo, Indonesia

Abstract. Widodo A, Lamid M, Effendi MH, Khailrullah AR, Kurniawan SC, Silaen OSM, Riwu KHP, Yustinasari LR, Afnani DA, Dameanti FNAEP, Ramandinianto SC. 2022. Antimicrobial resistance characteristics of multidrug and extended spectrum beta-lactamase producing Escherichia coli from several dairy farms in Probolinggo, Indonesia. Biodiversitas 23: 215-221. bacteria initially reside the digestive tract humans animals but are able to adapt new environments that different their initial habitat. The pathogenicity E. can occur when these grow more than normal limits, produce toxins, resistant certain types antibiotics. purpose this study was investigate antimicrobial MDR ESBL-producing Probolinggo district East Java province, A total 150 samples consisting 109 milk 41 environmental were used for isolation. TSIA IMViC biochemical tests identify bacteria. profile obtained through disc diffusion test on antibiotics, namely tetracycline, streptomycin, trimethoprim, chloramphenicol aztreonam. 3 or antibiotics defined as MDR. results isolation identification 124 (82.6%) isolates characterizing susceptibility showed 9 (7.26%) 2 (22.22%) ESBL by double-disc synergy (DDST). dominated pattern drug TE-S-W (tetracycline, trimethoprim) with a 8 (38.10%) isolates, followed TE-S-W-ATM aztreonam) one (4.76%) isolates. drugs (11.11%) sample (AL 30) trimethoprim). discovery at district, Java, Indonesia is matter concern requires real action reduce antibiotic resistance.